Awiti was born in Rachuonyo Sub County Homa Bay County in Kenya. Awiti attended his primary school at Mawego primary school in Rachuonyo. He then attended Mawego Secondary School. He then studied Electrical engineering at Mombasa Technical Training lnstitute. In 1984 he enrolled into the University of Machester studying Management Administration and graduate in 1987 with a master of Education.
Awiti began his career working for kenya's Ministry of public works as an Electrical inspector, he left after few years and began working at Mombasa polytechnic as a senior lecture . In 1993 he was appointed Country director of Marie Stopes Kenya where he served there till 2010.ln 2013 he was elected Governor of Homabay county.
On July 14,2015 Cyprian Awiti was summoned by the Senate committee on county public Account to explain how he spent Ksh 11.8 million on renovation of the Governor's Office through a tender given through restrictive process few days after his assumption of Office.