Genotype Compatibility: What You Need To Know Before Marriage

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One of the things to keep in mind when choosing your life partner is genotype. Unfortunately, many ignore this and go ahead in relationships. This is not to cause separation in relationships but to weigh the chances & possibilities of future health issues that can been avoided now.

What is genotype?

A genotype describes the gene – the functional unit of inheritance in an individual. Each genotype is unique and determines the outward appearance of every individual. Basically, genotypes are represented with alphabets, the common ones being A, C, and S. They are inherited from each parent and therefore exist in pairs such as AA, AC, AS, or SS. Those with AA are said to be normal. On the other hand, those with AC or AS are said to be carriers while SS are often called "sicklers".

How do I know my genotype?

The only way to determine one's genotype is by going to the hospital for a blood genotype test.

How do I know I'm compatible with my partner?

Those with AA are free to marry a person of any genotype. However, others are to be cautious of choosing life patners as this could raise a chance of having kids with abonormal genotype. The genotype chart is a simplified diagram to help one understand the compatibility of one's genotype with another's.

AA + AA = Excellent

AA + AS = Good

AA + SS = Fair

AA + AC = Good

AS + AS = Very Bad

AS + SS = Very Bad

AS + AC = Very Bad; Advice needed

SS + SS = Very Bad; Should be strictly avoided

AC + SS = Very Bad

AC + AC = Bad; Advice needed

In summary

🔸 Someone with AA can marry a fellow AA. Their kids would all be AA and and this is the most compatible genotypes.

🔸 Someone with AA can marry an AS. Their kids with AA and AS which is good.

🔸 Someone with AS should not marry a fellow AS. There is the risk of having children with SS.

🔸 Someone with SS should not marry a fellow SS. This is because all their kids will be SS. In this case, the kids suffer for it.

🔸 Anyone with a carrier of either C or S is advised against marrying a fellow carrier of any of the two genotypes.

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